Thermo Fisher Scientific SND1 Polyclonal Antibody
Thermo Fisher Scientific의 SND1 Polyclonal Antibody는 인간 SND1 단백질을 인식하는 Rabbit IgG 형 항체로, Western blot 및 Immunoprecipitation에 사용됩니다. 고순도 항원 친화 크로마토그래피로 정제되었으며, 293T 및 HepG2 세포에서 검증되었습니다. 연구용으로만 사용 가능합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:3,000
- Publications: View 1 publication
Immunoprecipitation (IP)
- Tested Dilution: 1:100–1:500
- Publications: View 1 publication
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published species | Not Applicable |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein encompassing a sequence within the center region of human SND1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.74 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7, with 20% glycerol |
| Contains | 0.025% ProClin 300 |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2607118 |
Product Specific Information
- Recommended positive controls: 293T and HepG2 cells
- Predicted reactivity: Mouse (100%), Rat (100%), Zebrafish (89%), Xenopus laevis (93%), Bovine (100%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
SND1/P100 (staphylococcal nuclease and tudor domain containing 1), also known as TudorSN, functions in the Pim-1 regulation of Myb activity and acts as a transcriptional activator of EBNA-2. It interacts with EAV, NSP1, GTF2E1, and GTF2E2, forming a ternary complex with Stat6 and POLR2A. The staphylococcal nuclease-like (SN) domains directly interact with amino acids 1099–1758 of CBP. SND1/P100 plays an important role in the assembly of Stat6 transcriptome and stimulates IL-4-dependent transcription by mediating interaction between Stat6 and CBP.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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