Thermo Fisher Scientific ADSL Monoclonal Antibody (05)
인간 ADSL/Adenylosuccinate Lyase 특이적 단클론 항체로 면역세포염색(ICC/IF)에 적합. 비결합형 액상 형태이며 1 mg/mL 농도. -20°C 보관, 동결·해동 반복 방지. 연구용으로만 사용 가능.
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Applications
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:20–1:100
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 05 |
| Immunogen | Recombinant Human ADSL / Adenylosuccinate Lyase Protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2912161 |
Product Specific Information
- Specificity: Human ADSL / Adenylosuccinate Lyase
Target Information
ADSL (adenylosuccinate lyase), also known as AMPS, ASL or ASASE, is a 484 amino acid protein that plays a role in purine biosynthesis and AMP formation from inosine monophosphate.
It catalyzes two key reactions in AMP biosynthesis:
- Removal of fumarate from succinylaminoimidazole carboxamide (SAICA) ribotide to produce aminoimidazole carboxamide ribotide (AICA).
- Removal of fumarate from adenylosuccinate to yield AMP.
Defects in the ADSL gene cause adenylosuccinase deficiency, an autosomal recessive disorder characterized by epilepsy, growth retardation, and muscular wasting. Multiple isoforms of ADSL exist due to alternative splicing.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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