Thermo Fisher Scientific CCRL2 Monoclonal Antibody (498321)
마우스 CCRL2 단백질을 인식하는 Rat IgG1 단클론 항체. ICC/IF 및 유세포분석(Flow Cytometry)에 적합. 단백질 A/G로 정제된 동결건조 형태로 제공되며, 재구성 후 0.5 mg/mL로 사용 가능. 연구용 전용 시약.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Immunocytochemistry (ICC/IF) | 8–25 µg/mL |
| Flow Cytometry (Flow) | 2.5 µg per million cells |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Host / Isotype | Rat / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 498321 |
| Immunogen | RBL-1 rat basophilic leukemia cell line transfected with mouse CCRL2/LCCR |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.5 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS with 5% trehalose |
| Contains | No Preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2610321 |
Product Specific Information
Reconstitute at 0.5 mg/mL in sterile PBS.
Target Information
CCRL2 (C-C chemokine receptor-like 2), also known as chemokine receptor X, human chemokine receptor (HCR), CRAM-A, or CRAM-B, is a seven-pass transmembrane protein expressed by monocytes, neutrophils, and dendritic cells of immune tissues (predominantly spleen, fetal liver, bone marrow, and lymph node).
It shares over 40% homology with other C-C chemokine receptors but lacks the conserved DRY motif, which is important for signaling and ligand binding.
C-C chemokine receptors are G-protein coupled, seven-pass transmembrane domain proteins whose main physiological role is to mediate chemotaxis of T cells and phagocytic cells to sites of inflammation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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