Thermo Fisher Scientific Phospho-Dab1 (Tyr232) Polyclonal Antibody
Phospho-Dab1 (Tyr232) 폴리클로날 항체로, 인간·마우스·랫트 시료에 반응합니다. Western blot, IHC, ICC, ELISA 등 다양한 응용에 적합하며, 단백질 A로 정제된 고순도 항체입니다. 뇌 발달 관련 Dab1 인산화 연구에 활용됩니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:200 |
| Immunohistochemistry (Frozen) (IHC-F) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH-conjugated synthetic phosphopeptide derived from human Dab1 around the phosphorylation site of Tyr232 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The laminar organization of multiple neuronal types in the cerebral cortex is required for normal cognitive function. In mice, the disabled-1 gene (Dab1) plays a central role in brain development, directing the migration of cortical neurons past previously formed neurons to reach their proper layer. This gene encodes a signal transducer protein that interacts with protein kinase pathways to regulate neuronal positioning in the developing brain. Alternatively spliced transcript variants have been reported, though their full-length forms remain undetermined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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