Thermo Fisher Scientific WNT6 Polyclonal Antibody
WNT6 단백질의 내인성 수준을 검출하는 Rabbit Polyclonal 항체. 인간 및 생쥐 반응성. IHC 및 IHC(Paraffin) 분석에 적합. 항원 친화 크로마토그래피로 정제된 고순도 항체로 안정적인 액상 형태로 제공.
- 카탈로그번호
- PA551340
- 판매단위
- pk
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Thermo Fisher Scientific WNT6 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Immunohistochemistry (IHC) | - | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:20–1:100 | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Published Species | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide of human WNT6 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2.4 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 40% glycerol |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2636787 |
Product Specific Information
The antibody detects endogenous levels of total WNT6 protein.
Target Information
The WNT gene family consists of structurally related genes encoding secreted signaling proteins. These proteins are involved in oncogenesis and various developmental processes, including regulation of cell fate and patterning during embryogenesis.
This gene is a member of the WNT gene family and is overexpressed in cervical cancer cell lines. It is strongly coexpressed with WNT10A in colorectal cancer cell lines, suggesting a key role in carcinogenesis.
Both genes are clustered in the chromosome 2q35 region. The protein encoded by this gene shares 97% amino acid identity with the mouse Wnt6 protein.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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