Thermo Fisher Scientific CYP2A6 Monoclonal Antibody (OTI2A8), TrueMAB
CYP2A6 단백질을 인식하는 Thermo Fisher Scientific의 단클론 항체. Western blot, IHC, ICC, Flow cytometry에 적합. Human 시료 반응성, Mouse IgG2b 형식. Affinity chromatography로 정제된 액상 항체로, -20°C에서 보관.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:150 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| Flow Cytometry (Flow) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2A8 |
| Immunogen | Full length human recombinant protein of human CYP2A6 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.86 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The CYP2A6 gene encodes a member of the cytochrome P450 superfamily of enzymes. These monooxygenases catalyze reactions involved in drug metabolism and synthesis of cholesterol, steroids, and other lipids. The protein localizes to the endoplasmic reticulum and its expression is induced by phenobarbital. CYP2A6 hydroxylates coumarin and metabolizes nicotine, aflatoxin B1, nitrosamines, and some pharmaceuticals. Certain allelic variants result in poor metabolizer phenotypes. The gene is part of a cluster of cytochrome P450 genes (CYP2A, CYP2B, CYP2F) on chromosome 19q and was formerly referred to as CYP2A3.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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