Thermo Fisher Scientific Caspase 4/5 p20 (Cleaved Asp270, Asp311) Polyclonal Antibody
Caspase 4/5 단백질의 절단형(p20, Asp270 및 Asp311) 검출용 항체로 인간 시료에 반응합니다. Western blot에 적합하며 항원 친화 크로마토그래피로 정제된 고품질 rabbit polyclonal IgG입니다. 액상 형태로 -20°C 보관하며 연구용으로만 사용됩니다.
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Thermo Fisher Scientific Caspase 4/5 p20 (Cleaved Asp270, Asp311) Polyclonal Antibody
Applications
- Western Blot (WB): 1:500–1:1,000 dilution
- Publications: [References not provided]
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide derived from human Caspase 4/5 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | Dulbecco’s PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2556422 |
Target Information
This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution phase of cell apoptosis. Caspases exist as inactive proenzymes composed of a prodomain and large/small protease subunits. Activation requires proteolytic processing at conserved internal aspartic residues to generate a heterodimeric enzyme. This caspase can cleave and activate its own precursor as well as caspase 1 precursor. Overexpression induces apoptosis. Alternative splicing produces distinct isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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