Thermo Fisher Scientific AMOTL1 Polyclonal Antibody
Rabbit polyclonal antibody against human AMOTL1 for Western blot applications. Recognizes N-terminal region (aa 144–193) of AMOTL1. High sequence homology across species. Supplied as liquid, 0.5 mg/mL, stored at -20°C. For research use only.
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Applications
- Western Blot (WB): 0.2–1 µg/mL
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Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the N-terminal of human AMOTL1 (aa 144–193) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2606805 |
Product Specific Information
Peptide sequence:
LTQEDPQMVY QSARQEPQGQ EHQVDNTVME KQVRSTQPQQ NNEELPTYEE
Sequence homology:
- Cow: 93%
- Dog: 79%
- Guinea Pig: 100%
- Human: 100%
- Mouse: 100%
- Rabbit: 100%
Target Information
The AMOTL1 protein is a peripheral membrane protein associated with tight junctions (TJs). TJs form apical junctional structures that regulate paracellular permeability and maintain cell polarity. AMOTL1 is related to angiomotin, an angiostatin-binding protein involved in endothelial cell migration and capillary formation. Two transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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