Thermo Fisher Scientific DTYMK Monoclonal Antibody (OTI2D1), TrueMAB
인간 DTYMK 단백질을 인식하는 Mouse IgG1 단클론 항체로, WB 및 ICC/IF에 사용 가능. Lyophilized 형태로 제공되며, PBS와 trehalose 버퍼에 보관. DNA 합성 관련 효소 DTYMK 연구에 적합.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:100
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2D1 |
| Immunogen | Full length human recombinant protein of human DTYMK produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform desalting using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
Thymidylate kinase (DTYMK) catalyzes the phosphorylation of dTMP to form dTDP in the dTTP synthesis pathway for DNA synthesis.
DTYMK is essential for DNA synthesis and plays an important role in the metabolism of pyrimidine analog drugs, including 5-Fluorouracil (5-FU), a chemotherapeutic agent used for solid tumors.
The human DTYMK gene was identified by functional complementation of a Saccharomyces cerevisiae cell cycle mutant (cdc8).
DTYMK mRNA levels and enzyme activities are regulated by cell cycle and growth pathways.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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