Thermo Fisher Scientific RPAP1 Polyclonal Antibody
Human RPAP1 단백질을 인식하는 Rabbit Polyclonal Antibody로, IHC(P) 및 ICC/IF에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, PBS 기반 용액에 40% 글리세롤과 0.02% sodium azide를 포함합니다. 연구용으로만 사용 가능합니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:1,000–1:2,500 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human RPAP1. Recombinant protein control fragment (Product # RP-98046) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.6 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2646709 |
Product Specific Information
Immunogen sequence:
HITAVLTKII ERDTSSVAVN LPVPSGVAFP AVFLRSRDTQ GKSATSGKRS IFAQEIAARR IAEAKGPSVG EVVPNVGPPE GAVTCETPTP RNQGCQLPGS SHSFQGPNLV TGKGL
Highest antigen sequence identity to the following orthologs:
- Mouse: 68%
- Rat: 68%
Target Information
RNA polymerases transcribe nuclear genes for ribosomal RNA and are integral components of ribosomal biogenesis.
- RNA polymerase I (Pol I): Located in the nucleolus; transcribes class I genes coding for large ribosomal RNA.
- RNA polymerase II (Pol II): Synthesizes mRNA.
- RNA polymerase III (Pol III): Transcribes class III genes encoding small ribosomal RNA molecules including tRNA and 5S rRNA.
RPAP1 (RNA polymerase II associated protein 1) is a 1,393 amino acid nuclear protein thought to connect Pol II to acetylated Histone H3 and regulators of protein complex formation.
A member of the RPAP1 family, RPAP1 exists as three alternatively spliced isoforms encoded by a gene located on human chromosome 15q15.1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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