Thermo Fisher Scientific NDUFA13 Monoclonal Antibody (6E1BH7)

Applications

Tested Dilution

Publications

Western Blot (WB)

1.0 µg/mL

-

Immunohistochemistry (IHC)

-

View 1 publication 1 publication

Immunocytochemistry (ICC/IF)

1.0 µg/mL

View 2 publications 2 publications

Flow Cytometry (Flow)

1 µg/mL

-

Product Specifications

Species Reactivity

Bovine, Human, Mouse, Rat

Published species

Rat

Host/Isotype

Mouse / IgG2b, kappa

Class

Monoclonal

Type

Antibody

Clone

6E1BH7

Immunogen

Full-length recombinant human GRIM-19 if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:NDUFA13,uniProtId:Q9P0J0-1,ncbiNodeId:9606,antigenRange:1-144,antigenLength:144,antigenImageFileName:43-8900_NDUFA13_Q9P0J0-1_House_mouse.svg,antigenImageFileNamePDP:43-8900_NDUFA13_Q9P0J0-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Ammonium sulfate precipitation

Storage buffer

HEPES buffered saline

Contains

0.02% sodium azide

Storage conditions

4° C, do not freeze

Shipping conditions

Wet ice

RRID

AB_2533544

Product Specific Information

Positive control: Human heart, Bovine heart, Rat heart, and Mouse heart isolated mitochondria, Human fibroblasts, HeLa cells

Target Information

A novel gene associated with Retinoid-IFN-induced Mortality (GRIM) GRIM-19 gene was identified. Antisense expression of GRIM-19 confers a strong resistance against IFN/RA-induced death by reducing the intracellular levels of GRIM-19 protein. Overexpression of GRIM-19 enhances cell death in response to IFN/RA. GRIM-19 is primarily a nuclear protein whose expression is induced by the IFN/RA combination. These data indicate that GRIM-19 is a novel cell death-regulatory molecule.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.