Thermo Fisher Scientific PD-L1 Monoclonal Antibody (OTI9E12), TrueMAB
인간 PD-L1 단백질(aa 19-239)을 인식하는 Mouse IgG1 단클론 항체. Western blot, Flow cytometry, ELISA, Luminex 등 다양한 응용 가능. 고순도 친화 크로마토그래피 정제, 1 mg/mL 농도. 연구용 전용 제품.
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Applications
| Application | Tested Dilution | Notes |
|---|---|---|
| Western Blot (WB) | 1:500 | |
| Flow Cytometry (Flow) | Assay-dependent | |
| ELISA | Assay-dependent | |
| Luminex (LUM) | Assay-dependent |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI9E12 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 19–239 of human PD-L1/CD274 produced in HEK293 cells |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Programmed death receptor ligand 1 (PD-L1, also called B7-H1) is a B7 family member that binds to the programmed death receptor 1 (PD-1), negatively regulating T-cell receptor (TCR) signaling. PD-L1 engagement decreases TCR-mediated proliferation and cytokine production. Its expression is abundant on many murine and human cancers and is upregulated by IFN-γ stimulation, suggesting an important role in tumor immune evasion.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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