Thermo Fisher Scientific Syncollin Polyclonal Antibody
Rabbit polyclonal antibody targeting human Syncollin (SYCN). Validated for Western blot at 1 µg/mL. Recognizes N-terminal region (aa 1–50) of SYCN. Supplied as liquid, 0.5 mg/mL in PBS with 2% sucrose. For research use only.
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Applications
- Western Blot (WB): Tested at 1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the N-terminal of human SYCN (aa 1–50) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2608030 |
Product Specific Information
- Peptide sequence:
MSPLRPLLLA LALASVPCAQ GACPASADLK HSDGTRTCAK LYDKSDPYYE - Sequence homology:
Cow: 100%; Dog: 86%; Human: 100%; Mouse: 79%; Pig: 86%; Rat: 79%
Target Information
Syncollin is a 134 amino acid, small peripheral membrane protein abundantly expressed in pancreatic acinar cells and is tightly associated with the lumenal side of the zymogen granule membrane. It contains intrachain disulfide bonds and associates with lipid rafts in a cholesterol-dependent manner. In pancreatic acinar cells, syncollin aids in exocytosis and contributes to the maturation and concentration of zymogens. It may also exhibit pore-forming activity on membranes and regulate exocytosis in some exocrine tissues.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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