Thermo Fisher Scientific Syncollin Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Synthetic peptide directed towards the N-terminal of human SYCN (aa 1-50). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:Syncollin,uniProtId:Q0VAF6-1,ncbiNodeId:9606,antigenRange:1-50,antigenLength:134,antigenImageFileName:PA5-45619_Syncollin_Q0VAF6-1_Rabbit.svg,antigenImageFileNamePDP:PA5-45619_Syncollin_Q0VAF6-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.5 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS with 2% sucrose

Contains

0.09% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2608030

Product Specific Information

Peptide sequence: MSPLRPLLLA LALASVPCAQ GACPASADLK HSDGTRTCAK LYDKSDPYYE

Sequence homology: Cow: 100%; Dog: 86%; Human: 100%; Mouse: 79%; Pig: 86%; Rat: 79%

Target Information

Syncollin is a 134 amino acid, small peripheral membrane protein abundantly expressed in pancreatic acinar cells and is tightly associated with the lumenal side of the zymogen granule membrane. It contains intrachain disulfide bonds. Syncollin is also known to associate with lipid rafts in a cholesterol-dependent manner. In pancreatic acinar cells, syncollin helps in exocytosis and also plays a role in maturation and/or concentration of zymogens in zymogen granules. Reports suggest that syncollin may also have a pore-forming activity on membranes and regulate exocytosis insome exocrine tissues.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.