Thermo Fisher Scientific CENPT Polyclonal Antibody
Thermo Fisher Scientific의 CENPT Polyclonal Antibody는 인간 CENPT 단백질의 C-말단 영역을 표적으로 하는 토끼 유래 IgG 항체입니다. Western blot에 적합하며, 고순도 친화 크로마토그래피로 정제되었습니다. PBS 기반 완충액에 보관하며 연구용으로 사용됩니다.
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Applications
- Western Blot (WB)
Tested Dilution: 1.0 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the C-terminal region of human CENPT |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2689808 |
Product Specific Information
This target displays homology in the following species:
- Cow: 85%
- Dog: 86%
- Guinea Pig: 79%
- Human: 100%
- Mouse: 93%
- Pig: 85%
- Rabbit: 92%
- Rat: 100%
Target Information
CENPT is a component of the CENPA-NAC (nucleosome-associated) complex, which plays a central role in kinetochore protein assembly, mitotic progression, and chromosome segregation.
The CENPA-NAC complex recruits the CENPA-CAD complex and may assist in incorporating newly synthesized CENPA into centromeres.
CENPT forms part of the heterotetrameric CENP-T-W-S-X complex that binds and supercoils DNA, contributing to kinetochore assembly and function.
It is essential for normal chromosome organization and mitotic progression.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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