
Thermo Fisher Scientific Phospho-Caldesmon (Ser759) Polyclonal Antibody
Phospho-Caldesmon (Ser759)을 인식하는 Rabbit Polyclonal 항체로, IHC(P)에서 1:50–1:100 희석 비율로 사용 가능. 인간 Caldesmon의 Ser759 인산화 부위 기반 합성 펩타이드로부터 제작. 비결합형 액상 형태이며, -20°C에서 보관. 연구용으로만 사용.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:100
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic phosphopeptide derived from human Caldesmon around the phosphorylation site of Ser759 (N-K-SP-P-A) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2556331 |
Target Information
Caldesmon is a developmentally regulated protein involved in smooth muscle and non-muscle contraction. Two closely related variants of human caldesmon have been identified which differ in their electrophoretic mobility and cellular distribution.
The h-caldesmon variant (120–150 kDa) is predominantly expressed in smooth muscle, whereas l-caldesmon (70–80 kDa) is found in non-muscle tissue and cells. Neither of the two variants has been detected in skeletal muscle.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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