Thermo Fisher Scientific Sialosyl-Tn Antigen Monoclonal Antibody (STn 219)

Applications

Western Blot (WB)

• Tested Dilution: 1:50–1:100
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Immunohistochemistry (IHC)

• Tested Dilution: Assay-dependent
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Immunocytochemistry (ICC/IF)

• Tested Dilution: Assay-dependent
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Product Specifications

Product Specific Information

• Recommended positive controls: Human gastrointestinal tumor, prostate, ovary carcinoma
• This antibody stains colon carcinomas and ovarian mucinous carcinomas, showing apical cytoplasmic, apical membrane, and luminal staining patterns.
• It is negative with the majority of adult tissue sections.

Target Information

Sialosyl Tn antigen (CD175s) is expressed in the majority of colon, gastric, breast, and lung carcinomas.
It shows limited or absent expression in normal colon, pancreas, stomach, ovary, and prostate tissues.
This antigen is detected in several adenocarcinomas and serves as a useful marker for poorly differentiated colon adenocarcinoma.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.