Thermo Fisher Scientific Sialosyl-Tn Antigen Monoclonal Antibody (STn 219)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:50-1:100

View 1 publication 1 publication

Immunohistochemistry (IHC)

Assay-dependent

-

Immunocytochemistry (ICC/IF)

Assay-dependent

-

Product Specifications

Species Reactivity

Human, Sheep

Published species

Not Applicable

Host/Isotype

Mouse / IgG1

Class

Monoclonal

Type

Antibody

Clone

STn 219

Immunogen

Ovine submaxillary mucin (OSM)

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.2 mg/mL

Purification

Protein A

Storage buffer

PBS, pH 7.2, with 1% BSA

Contains

0.05% sodium azide

Storage conditions

4° C, do not freeze

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2264594

Product Specific Information

Recommended positive controls: Human gastrointestinal tumor, prostate, ovary ca..

This antibody stains colon carcinomas and ovarian mucinous carcinomas producing apical cytoplasmic, apical membrane and luminal staining patterns. It is negative with majority of adult tissue sections.

Target Information

Sialosyl Tn antigen, also known as CD175s, is expressed in the majority of colon, gastric, breast, and lung carcinoma. The sialosyl Tn has limited expression to being absent in normal colon, pancreas, stomach, ovary, and prostate. This antigen is detected in several adenocarcinomas. It appears to be useful marker for poorly differentiated colon adenocarcinoma.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.