Thermo Fisher Scientific FGFR1OP Polyclonal Antibody

Applications

Western Blot (WB)

• Tested Dilution: 1:500–1:3,000

Immunohistochemistry (Paraffin) (IHC (P))

• Tested Dilution: 1:100–1:1,000

Product Specifications

Product Specific Information

• Recommended positive controls: Jurkat, Raji
• Predicted reactivity: Human (99%)
• Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Target Information

This gene encodes a largely hydrophilic protein postulated to be a leucine-rich protein family member.
A t(6;8)(q27;p11) chromosomal translocation, fusing this gene and the fibroblast growth factor receptor 1 (FGFR1) gene, has been found in cases of myeloproliferative disorder.
The resulting chimeric protein contains the N-terminal leucine-rich region of this encoded protein fused to the catalytic domain of FGFR1.
This gene is thought to play an important role in normal proliferation and differentiation of the erythroid lineage.
Alternatively spliced transcript variants that encode different proteins have been identified.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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