Thermo Fisher Scientific SLC39A4 Polyclonal Antibody
SLC39A4 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, 인간 시료에 반응합니다. Western blot에 적합하며, 고순도 Affinity chromatography로 정제되었습니다. Zinc transporter ZIP4 연구용으로 사용됩니다.
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Applications
- Western Blot (WB): 0.2–1.0 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the N-terminal region of human SLC39A4 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2689364 |
Product Specific Information
This target displays homology in the following species:
- Human: 100%
- Rabbit: 92%
- Rat: 100%
Target Information
The zinc transporter ZIP4 (SLC39A4) is a member of a family of divalent ion transporters. Zinc is an essential ion for cells and plays significant roles in growth, development, and differentiation. ZIP4 was initially identified as a zinc-uptake transporter in the intestine and as a candidate gene for acrodermatitis enteropathica (AE), a rare inherited defect in dietary zinc absorption. Aberrant expression of ZIP4 has been linked to cancer, particularly pancreatic cancer progression and aggressiveness. ZIP4 activation in hepatocellular carcinomas represses apoptosis, enhances cell cycle progression, and increases migration, suggesting a role in multiple cancer types.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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