Thermo Fisher Scientific MB67 Monoclonal Antibody (OTI1C6)
Human NR1I3 단백질(아미노산 1-236)을 인식하는 Mouse IgG1 단클론 항체로, WB 및 IHC(P) 실험에 적합. 1 mg/mL 농도의 액상 형태로 PBS/BSA/glycerol 버퍼에 보존. 약물 대사 및 빌리루빈 제거 관련 핵심 전사 조절 인자 연구용.
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Applications
- Western Blot (WB): 1:2,000
- Immunohistochemistry (Paraffin) (IHC (P)): 1:150
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1C6 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 1–236 of NR1I3 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2724653 |
Target Information
This gene encodes a member of the nuclear receptor superfamily and is a key regulator of xenobiotic and endobiotic metabolism. The protein binds to DNA as a monomer or a heterodimer with the retinoid X receptor and regulates transcription of target genes involved in drug metabolism and bilirubin clearance, such as cytochrome P450 family members. Unlike most nuclear receptors, this transcriptional regulator is constitutively active in the absence of ligand but is regulated by both agonists and inverse agonists.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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