Thermo Fisher Scientific RAD23B Monoclonal Antibody (OTI7F11), TrueMAB
RAD23B 단백질을 인식하는 Mouse IgG1 단클론 항체로, Western blot에 적합합니다. 인간 RAD23B(aa 1–253) 재조합 단백질로 면역화되었으며, 액상 형태로 제공됩니다. 고순도 정제 및 안정적 저장이 가능하여 DNA 손상 연구에 활용됩니다.
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Applications
- Western Blot (WB)
Tested Dilution: 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI7F11 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 1–253 of human RAD23B produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The RAD23B protein is one of two human homologs of Saccharomyces cerevisiae Rad23, which participates in nucleotide excision repair (NER). It complements the NER defect of xeroderma pigmentosum group C (XP-C) cell extracts and interacts with 3-methyladenine-DNA glycosylase (MPG), suggesting a role in DNA damage recognition during base excision repair.
RAD23B contains an N-terminal ubiquitin-like domain that interacts with the 26S proteasome, implying involvement in the ubiquitin-mediated proteolytic pathway.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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