Thermo Fisher Scientific Desmin Polyclonal Antibody
Desmin 단백질을 인식하는 Rabbit Polyclonal 항체로, WB, IHC, ICC/IF, IP 등 다양한 응용에 사용 가능. 근육세포 특이적 단백질 연구에 적합하며, 액상 형태로 제공되고 -20°C에서 보관. 연구용 전용 제품.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:500–1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
| Immunoprecipitation (IP) | 5–10 µL/mg of lysate |
Product Specifications
| Specification | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide corresponding to the C-terminus of the Mouse Desmin/DES |
| Conjugate | Unconjugated |
| Form | Liquid |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2902516 |
Target Information
Desmin (approximately 53 kDa) is a muscle-specific intermediate filament protein expressed predominantly in cardiac, skeletal, and smooth muscle cells. Its expression is developmentally and tissue-specific, being induced during terminal muscle differentiation. In skeletal and cardiac muscle, desmin localizes in the Z-disk and intercalated disk regions. Expression in smooth muscle is more heterogeneous. Coexpression of vimentin and desmin has been observed in muscle-derived tumors such as rhabdomyosarcomas and leiomyosarcomas. Altered desmin distribution has been reported during myocardial dysfunction.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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