Thermo Fisher Scientific Carbonic Anhydrase IX Monoclonal Antibody (GT14212)
인간 Carbonic Anhydrase IX 단백질을 인식하는 마우스 단클론 항체. Western blot 및 면역세포염색에 적합. 단백질 G로 정제된 액상 형태로 제공되며, 4°C 단기 보관 또는 -20°C 장기 보관 가능. 연구용으로만 사용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:3,000 |
| Immunocytochemistry (ICC/IF) | 1:100–1:1,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | GT14212 |
| Immunogen | Recombinant protein encompassing a sequence within the N-terminus region of human Carbonic Anhydrase IX |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage buffer | PBS |
| Contains | No preservative |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2787118 |
Product Specific Information
- Keep as concentrated solution.
- Positive Control: A431.
- Store product as a concentrated solution.
- Centrifuge briefly prior to opening the vial.
Target Information
Carbonic anhydrase (CA) is an enzyme that catalyzes the rapid interconversion of carbon dioxide and water into carbonic acid, protons, and bicarbonate ions. It is abundant in all mammalian tissues.
CA IX is one of the most inducible genes under hypoxic conditions due to its stability and membrane localization.
Carbonic anhydrases regulate pH in normal tissues by controlling hydrogen ion flux. Under hypoxia, inhibition of CA IX increases cell death, making CA IX a reliable histochemical marker of hypoxia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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