Thermo Fisher Scientific CALU Polyclonal Antibody
Thermo Fisher Scientific의 CALU Polyclonal Antibody는 인간 Calumenin 단백질을 표적으로 하는 토끼 유래 IgG 항체입니다. Western blot 및 Immunoprecipitation에 적합하며, 항원 친화 크로마토그래피로 정제되었습니다. 액상 형태로 제공되며 4°C에서 보관합니다.
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Applications
Western Blot (WB)
- Assay-dependent
Immunoprecipitation (IP)
- 2–10 µg/mg lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 1 to 50 of human Calumenin |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | Phosphate/Tris citrate, pH 7–8 |
| Contains | 0.09% sodium azide |
| Storage conditions | 4°C |
| Shipping conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Based on 100% sequence identity, predicted to react with Mouse, Rat, Zebrafish, X. laevis, X. tropicalis, Bovine, Rabbit, Golden hamster, and Orangutan
Target Information
Calumenin is a 315 amino acid Ca²⁺-binding member of the CREC, EF-hand protein family. It is a secreted protein containing six Ca²⁺-binding (EF-hand) motifs and is expressed in the lumen of the endoplasmic reticulum (ER) and Golgi apparatus. In the presence of Ca²⁺, Calumenin interacts with serum amyloid P component (SAP), potentially playing a role in immunological defense and amyloidosis. It inhibits the vitamin K-dependent γ-carboxylation system, affecting Gla-containing protein formation. Calumenin may also be involved in thrombosis and wound healing through autocrine or paracrine mechanisms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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