Thermo Fisher Scientific POU6F1 Polyclonal Antibody
Thermo Fisher Scientific의 POU6F1 폴리클로날 항체로, 인간·마우스·랫트 시료에 반응합니다. Western blot, ICC/IF, ELISA에 사용 가능하며, 고순도의 친화 크로마토그래피 정제 제품입니다. PBS/glycerol 완충액에 보관되며, 연구용으로 적합합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:50–1:100 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 1–301 of human POU6F1 (NP_002693.3) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.49 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2855614 |
Product Specific Information
Immunogen sequence:
MPGISSQILT NAQGQVIGTL PWVVNSASVA APAPAQSLQV QAVTPQLLLN AQGQVIATLA SSPLPPPVAV RKPSTPESPA KSEVQPIQPT PTVPQPAVVI ASPAPAAKPS ASAPIPITCS ETPTVSQLVS KPHTPSLDED GINLEEIREF AKNFKIRRLS LGLTQTQVGQ ALTATEGPAY SQSAICRFEK LDITPKSAQK LKPVLEKWLN EAELRNQEGQ QNLMEFVGGE PSKKRKRRTS FTPQAIEALN AYFEKNPLPT GQEITEIAKE LNYDREVVRV WFCNRRQTLK NTSKLNVFQI P
Target Information
Brn-5 (Brain-5), also known as POU6F1, MPOU, or TCFB1, is a widely expressed protein that during embryogenesis is exclusively found in the developing brain and spinal cord. It contains two DNA-binding domains — the POU-specific domain and the POU homeodomain — each with an HTH (helix-turn-helix) motif. Brn-5 binds to CRH (corticotrophin-releasing hormone) elements with high affinity and can enhance Prolactin gene expression and activate Pit-1 expression.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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