Thermo Fisher Scientific Bovine Factor X Native Protein
소의 Factor X 단백질로, 다양한 면역학적 분석의 양성 대조군으로 사용 가능. 6.0 mg/mL 농도의 액상 형태이며, SDS-PAGE로 정제됨. 50% 글리세롤 완충용액에 보관되며, -20°C에서 냉동-해동 반복을 피해야 함.
- 카탈로그번호
- RP43073
- 카테고리
- Protein
- 판매단위
- pk
카탈로그
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Applications
- Control (Ctrl): Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species | Bovine |
| Molecular Weight | 55.1 kDa |
| Class | Native |
| Type | Protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 6.0 mg/mL |
| Purification | SDS-PAGE |
| Storage Buffer | 50% water with 50% glycerol |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
Product Specific Information
RP-43073 contains native bovine Factor X protein.
RP-43073 may be used as a positive control in many immunological assays.
Target Information
F10 undergoes multiple processing steps before its preproprotein is converted to a mature two-chain form by the excision of the tripeptide RKR. Two chains of the factor are held together by one or more disulfide bonds; the light chain contains two EGF-like domains, while the heavy chain contains the catalytic domain which is structurally homologous to those of the other hemostatic serine proteases.
The mature factor is activated by the cleavage of the activation peptide by factor IXa (intrinsic pathway) or by factor VIIa (extrinsic pathway). The activated factor then converts prothrombin to thrombin in the presence of factor Va, Ca²⁺, and phospholipid during blood clotting.
Mutations of this gene result in factor X deficiency, a hemorrhagic condition of variable severity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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