
Thermo Fisher Scientific KLK8 Monoclonal Antibody (OTI11F7), TrueMAB
KLK8 단백질을 인식하는 마우스 단클론 항체로 Western blot 및 IHC(P) 분석에 적합. 인간 시료에 반응하며, 1 mg/mL 농도의 액상 형태로 제공. 친화 크로마토그래피로 정제되었으며, PBS/BSA/glycerol 완충액에 보관. 연구용으로만 사용 가능.
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Applications
- Western Blot (WB): 1:2,000
- Immunohistochemistry (Paraffin) (IHC (P)): 1:150
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI11F7 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 33–260 of human KLK8 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Kallikreins are a subgroup of serine proteases with diverse physiological functions. Many kallikreins are implicated in carcinogenesis and may serve as biomarkers for cancer and other diseases. The KLK8 gene is one of fifteen kallikrein subfamily members located in tandem on chromosome 19. The encoded protein may participate in proteolytic cascades in the skin and serve as a biomarker for ovarian cancer. Alternate splicing results in multiple transcript variants encoding different isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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