Thermo Fisher Scientific Neogenin Polyclonal Antibody
Thermo Fisher Scientific의 Neogenin Polyclonal Antibody는 인간 단백질에 반응하는 토끼 IgG 항체로, IHC(P)에서 1:20~1:50 희석 비율로 사용됩니다. 항원 친화 크로마토그래피로 정제되었으며, PBS와 글리세롤 버퍼에 보관됩니다. 연구용으로 적합합니다.
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Applications
- Immunohistochemistry (Paraffin) (IHC (P)): 1:20–1:50
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human Neogenin. Recombinant protein control fragment (Product #RP-95256). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.05 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2644615 |
Product Specific Information
Immunogen sequence:
NSKSIMIHWQ PPAPATQNGQ ITGYKIRYRK ASRKSDVTET LVSGTQLSQL IEGLDRGTEY NFRVAALTIN GTGPATDWLS AETFE
Highest antigen sequence identity to the following orthologs:
- Mouse: 93%
- Rat: 93%
Target Information
The protein encoded by this gene mediates transcriptional control by interaction with the activation function 2 (AF2) region of several nuclear receptors, including the estrogen, retinoic acid, and vitamin D3 receptors.
The protein localizes to nuclear bodies and is thought to associate with chromatin and heterochromatin-associated factors.
It is a member of the tripartite motif (TRIM) family, which includes three zinc-binding domains (RING, B-box type 1, B-box type 2) and a coiled-coil region.
Two alternatively spliced transcript variants encoding different isoforms have been described for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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