Thermo Fisher Scientific NQO1 Polyclonal Antibody
Thermo Fisher Scientific의 NQO1 Polyclonal Antibody는 인간, 마우스, 랫트에 반응하며 WB, IHC, ICC/IF 등 다양한 응용에 적합합니다. 합성 펩타이드 면역원 기반의 고순도 항체로, 내인성 NQO1 단백질 검출에 유용합니다. 연구용으로만 사용 가능합니다.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:2,000 | - |
| Immunohistochemistry (IHC) | - | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 | View 1 publication |
| Immunocytochemistry (ICC/IF) | 1:100–1:400 | - |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human NQO1 (Accession P15559), corresponding to amino acid residues V243–K274 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2900301 |
Product Specific Information
Antibody detects endogenous levels of total NQO1.
Target Information
NQO1 is a member of the NAD(P)H dehydrogenase (quinone) family and a cytoplasmic 2-electron reductase. This FAD-binding protein forms homodimers and reduces quinones to hydroquinones. NQO1’s enzymatic activity prevents the one-electron reduction of quinones that results in the production of radical species. Altered expression of this protein has been observed in many tumors and is also associated with Alzheimer’s disease (AD).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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(이미지 파일명: PA5-115666_NQO1_P15559-1_Rabbit.svg, PA5-115666_NQO1_P15559-1_Rabbit_PDP.jpeg)
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