Thermo Fisher Scientific CD122 Monoclonal Antibody (D4)
인간 CD122 단백질을 표적으로 하는 마우스 모노클로날 항체로, Western blot에 적합합니다. Recombinant Human IL2Rb 단백질을 면역원으로 사용하였으며, 단백질 A/G로 정제된 액상 형태입니다. 단기 4°C, 장기 -20°C 보관 권장.
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Applications
- Western Blot (WB): 0.01–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | D4 |
| Immunogen | Recombinant Human IL2Rb protein (Ala27–Thr240, Accession #P14784) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS (pH 7.4) with 50% glycerol |
| Contains | 0.05% Proclin 300 |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_3091299 |
Target Information
CD122 (Interleukin 2 receptor) is involved in T cell-mediated immune responses, primarily expressed in the hematopoietic system and exists in three forms:
- Low affinity form: Monomer of the alpha subunit, not involved in signal transduction
- Intermediate affinity form: Alpha/beta heterodimer
- High affinity form: Alpha/beta/gamma heterotrimer
Both intermediate and high affinity forms participate in receptor-mediated endocytosis and mitogenic signal transduction.
The CD122 gene encodes the beta subunit, a type I membrane protein.
Dysfunction of CD122 is associated with oligoarticular juvenile idiopathic arthritis and rheumatoid factor negative juvenile idiopathic arthritis.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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