Thermo Fisher Scientific RRAD Polyclonal Antibody
RRAD 단백질을 인식하는 Rabbit Polyclonal 항체로 Western blot, IHC, ICC/IF에 적합. 인간 RAD 내부 영역 유래 합성 펩타이드로부터 제작됨. 액상 형태로 제공되며 -20°C에서 보관. 연구용으로만 사용 가능.
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- PA539199
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- pk
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:100 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide derived from the internal region of human RAD |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2555791 |
Target Information
The Ras-encoded family of proteins bind GDP and GTP with high affinity and possess low intrinsic GTPase activity, which increases significantly upon interaction with cytosolic GTPase activating protein (GAP). Members include H-Ras, K-Ras, N-Ras, M-Ras, R-Ras, ERas, Rheb, TC21, RASL11B, and Rad (Ras associated with diabetes) GTPase.
Rad GTPase is a GTP-binding protein similar to Ras but with unique characteristics. Unlike other small GTPases, Rad GTPase lacks typical prenylation motifs at its C-terminus. It binds calmodulin, inhibits vascular lesion formation, exhibits low intrinsic GTPase activity, and cannot be stimulated by known GAP molecules. Rad GTPase is expressed in skeletal muscle, cardiac muscle, and lung tissues, and is overexpressed in skeletal muscle tissue of individuals with type II diabetes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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