Thermo Fisher Scientific SYP Monoclonal Antibody (OTI1G6), TrueMAB
Synaptophysin 단백질을 인식하는 Mouse monoclonal antibody로, Western blot 및 Immunocytochemistry에 적합. Human 시료에 반응하며, 고순도의 affinity chromatography로 정제됨. PBS/BSA/glycerol buffer에 보관되며 -20°C에서 안정적.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:4,000 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| Miscellaneous PubMed (Misc) | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Not Applicable |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1G6 |
| Immunogen | Full length human recombinant protein of human SYP produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Synaptophysin is a calcium-binding integral membrane glycoprotein found in presynaptic vesicles of nearly all neurons. It possesses four transmembrane domains and forms a complex with dynamin at high calcium concentrations, suggesting a role in synaptic vesicle endocytosis. Additionally, it participates in regulating short- and long-term synaptic plasticity. Synaptophysin is widely used as a marker for nerve terminals and in distinguishing neuroendocrine tumors. Mutations in this gene are associated with mental retardation, X-linked 96.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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