Thermo Fisher Scientific PAX6 (Stem Cell Marker) Monoclonal Antibody (SPM612)
PAX6 단백질을 인식하는 단클론 항체로, 줄기세포 및 신경계 발달 연구에 적합. IHC, ICC, Flow Cytometry 등 다양한 응용 가능. 인간 시료 반응성, Mouse IgG1 아이소타입. 단백질 A/G 정제, 4°C 보관.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 1–2 µg/mL |
| Immunocytochemistry (ICC/IF) | 1–2 µg/mL |
| Flow Cytometry (Flow) | 1–2 µg/10⁶ cells |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | SPM612 |
| Immunogen | Recombinant fragment (N-terminus, aa 1–300) of human PAX6 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The PAX6 gene encodes paired box gene 6, a human homolog of the Drosophila gene prd. This gene contains both a paired box domain and a homeobox domain, which bind DNA and regulate transcription. PAX6 is expressed in the developing nervous system and eyes. Mutations in PAX6 are associated with ocular disorders such as aniridia and Peter’s anomaly. Multiple alternatively spliced transcript variants exist.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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