Thermo Fisher Scientific Fumarase Monoclonal Antibody (OTI1F10)
Thermo Fisher Scientific의 Fumarase Monoclonal Antibody (OTI1F10)은 인간, 마우스, 랫, 개에 반응하는 단클론 항체로 다양한 면역분석(WB, IHC, ICC/IF, Flow)에 적합합니다. 고순도 Affinity Chromatography 정제, 안정적인 PBS/BSA/glycerol 저장용액 구성으로 연구용에 최적화되어 있습니다.
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Applications 및 Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| Flow Cytometry (Flow) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Dog, Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1F10 |
| Immunogen | Full length human recombinant protein of FH produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2723196 |
Target Information
The protein encoded by this gene is an enzymatic component of the tricarboxylic acid cycle (Krebs cycle) and catalyzes the formation of L-malate from fumarate. It exists in both cytosolic and N-terminal extended forms, differing only in translation start site. The extended form is targeted to the mitochondrion, where removal of the extension generates the same form found in the cytoplasm. It functions as a homotetramer and mutations can cause fumarase deficiency leading to progressive encephalopathy.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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