Thermo Fisher Scientific TFIP11 Polyclonal Antibody
Human TFIP11 단백질을 인식하는 Rabbit Polyclonal Antibody로 Western Blot 및 IHC(P) 검증 완료. Protein A 및 항원 친화 크로마토그래피로 정제된 액상형 항체. PBS 버퍼에 보관하며 단기 4°C, 장기 -20°C 저장 권장. 연구용으로만 사용.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:25 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide between 42–70 amino acids from the N-terminal region of human TFIP11 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein A, Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2634730 |
Product Specific Information
Predicted to react with monkey based on sequence homology.
Target Information
Involved in pre-mRNA splicing, specifically in spliceosome disassembly during late-stage splicing events. Intron turnover proceeds through reactions in two lariat-intron associated complexes termed Intron Large (IL) and Intron Small (IS). In cooperation with DHX15, TFIP11 mediates the transition of the U2, U5, and U6 snRNP-containing IL complex to the snRNP-free IS complex, leading to efficient debranching and turnover of excised introns. May play a role in the differentiation of ameloblasts and odontoblasts or in the formation of the enamel extracellular matrix.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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