Thermo Fisher Scientific CD55 Polyclonal Antibody
상품 옵션 정보 | ||||||||
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카탈로그 번호 | CAS 번호 | 설명 | 상태 | 단위 | 판매가 | 할인가 | 가격(VAT포함) | 수량 / 장바구니 / 찜 |
PA578991 | - | Thermo Fisher Scientific PA578991 CD55 Polyclonal Antibody 100 ug pk | 재고문의 | pk | 570,000원 | - | 627,000원 |
다른 상품 둘러보기
Applications
Tested Dilution
Publications
Western Blot (WB)
0.1-0.5 µg/mL
Immunohistochemistry (IHC)
2 µg/mL
Immunohistochemistry (Paraffin) (IHC (P))
0.5-1 µg/mL
Immunocytochemistry (ICC/IF)
2 µg/mL
Flow Cytometry (Flow)
1-3 µg/1x10^6 cells
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit / IgG
Class
Polyclonal
Type
Antibody
Immunogen
E.coli-derived human CD55 recombinant protein (Position: D35-K347). if (typeof window.$mangular === undefined
|| !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{
targetFamily:
CD55,
uniProtId:
P08174-1,
ncbiNodeId:
9606,
antigenRange:
35-347,
antigenLength:
381,
antigenImageFileName:
PA5-78991_CD55_P08174-1_Rabbit.svg,
antigenImageFileNamePDP:
PA5-78991_CD55_P08174-1_Rabbit_PDP.jpeg,
sortOrder:
1}\]
; $mangular.isB2BCMGT = false
; $mangular.isEpitopesModalImageMultiSizeEnabled = true
;
View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}
Conjugate
Unconjugated Unconjugated Unconjugated
Form
Lyophilized
Concentration
500 µg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS with 5mg BSA
Contains
0.05mg sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2746107
Product Specific Information
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Target Information
CD55 (decay-accelerating factor, DAF) is a GPI-anchored membrane glycoprotein that protects autologous cells from classical and alternative pathway of complement cascade. Bidirectional interactions between CD55 and CD97 are involved in T cell regulation and CD55 can regulate complement when bound to CD97. In tumors, CD55 promotes neoangiogenesis, tumorigenesis, invasiveness and evasion of apoptosis. CD55 is a 70 kDa glycoprotein (in erythrocytes) anchored in the membrane by glycosylphosphatidylinositol tail. In other cells, the apparent molecular weight is somewhat larger for CD55 and has a substantial content of O-glycans. CD55 binds to activated C4b or C3b complement fragments on the cell surface, preventing the assembly and accelerating the decay of both classical and alternative pathways. CD55 carries the Cromer related blood group antigens. Two alternatively spliced transcripts encoding CD55 have been identified, and the predominant transcript encodes a membrane-bound protein expressed on cells exposed to plasma component proteins but an alternatively spliced transcript produces a soluble protein present at much lower levels. CD55 has been studied to have a role in prostate cancer growth and survival.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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