Thermo Fisher Scientific ORAI2 Polyclonal Antibody
Rabbit polyclonal antibody targeting mouse ORAI2 (aa 16–32). Validated for WB and IHC at 1:200 dilution. Lyophilized form, 0.8 mg/mL concentration, stored at -20°C. Enables study of Ca++ channel regulation and immune cell signaling.
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Thermo Fisher Scientific ORAI2 Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:200 |
| Immunohistochemistry (IHC) | 1:200 |
Product Specifications
| Property | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide CPEPGHKGMDYRDWVRR, corresponding to amino acid residues 16–32 of mouse Orai2 |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.8 mg/mL |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2736277 |
Product Specific Information
Product is shipped at room temperature as a lyophilized powder and should be stored at -20°C upon receipt.
Reconstitution: add 50 µL of deionized water.
Target Information
Antigen stimulation of immune cells triggers Ca++ entry through Ca++ release-activated Ca++ (CRAC) channels.
ORAI2 is one of two mammalian homologs to ORAI1, a four-transmembrane spanning protein essential for CRAC channel function.
Like ORAI1, ORAI2 functions as a highly selective Ca++ plasma membrane channel gated through interactions with STIM1, the store-activated endoplasmic reticulum Ca++ sensor, though with lesser efficacy than ORAI1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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