Thermo Fisher Scientific Human IL17RA Synthetic Peptide
인간 IL17RA의 아미노 말단 18개 아미노산 서열에 해당하는 합성 펩타이드입니다. IL-17RA 항체의 차단 실험에 사용 가능하며, 염증 및 자가면역 연구에 적합합니다. PBS(pH 7.2)와 0.1% BSA 저장용액에 용해되어 있으며, -20°C에서 보관합니다.
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Thermo Fisher Scientific Human IL17RA Synthetic Peptide
Applications
- Control (Ctrl): Assay-dependent
- Blocking Assay (BLOCK): Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Purified |
| Storage Buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
Product Specific Information
This peptide corresponds to 18 amino acids near the amino terminus of IL-17RA.
PEP-1614 can be used as a blocking peptide with polyclonal antibody PA5-34571.
For use as a blocking peptide in Western blot, incubate the peptide with equal volume of antibody for 30 min at 37ºC.
Target Information
Interleukin 17A (IL-17A) is a proinflammatory cytokine secreted by activated T-lymphocytes. It induces maturation of CD34-positive hematopoietic precursors into neutrophils.
IL-17RA is a type I membrane glycoprotein that binds with low affinity to IL-17A and IL-17F.
IL-17A and its receptor are implicated in inflammatory and autoimmune diseases such as rheumatoid arthritis.
Defects in IL-17RA cause familial candidiasis type 5 (CANDF5), characterized by altered immune responses and impaired fungal clearance.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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