
Thermo Fisher Scientific NKX2 Monoclonal Antibody (UMAB162), UltraMAB
Human NKX2-1 단백질을 인식하는 Mouse IgG1 단클론 항체로, IHC(P)에서 1:200 희석으로 사용 가능. 친화 크로마토그래피로 정제되었으며 PBS/BSA/glycerol buffer에 보존. -20°C에서 보관하며 연구용으로 적합.
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Applications
Immunohistochemistry (Paraffin) [IHC (P)]
- Tested Dilution: 1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | UMAB162 |
| Immunogen | Full length human recombinant protein of human NKX2-1 (NP_003308) produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5–1.0 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C, Avoid freeze/thaw cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Target Information
This gene encodes a protein initially identified as a thyroid-specific transcription factor. The encoded protein binds to the thyroglobulin promoter and regulates the expression of thyroid-specific genes, as well as genes involved in morphogenesis. Mutations and deletions in this gene are associated with benign hereditary chorea, choreoathetosis, congenital hypothyroidism, and neonatal respiratory distress, and may be linked to thyroid cancer. Multiple transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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