Thermo Fisher Scientific PTGR2 Polyclonal Antibody
Thermo Fisher Scientific의 PTGR2 폴리클로날 항체는 돼지 단백질에 반응하며 Western blot에 최적화되어 있습니다. 0.5 mg/mL 농도의 액상 형태로 제공되며, TBS(pH 7.3) 버퍼와 0.5% BSA를 포함합니다. 연구용으로만 사용 가능합니다.
- 카탈로그번호
- PA5143285
- 판매단위
- pk
카탈로그
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Applications
Western Blot (WB)
- Tested Dilution: 1–3 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Pig |
| Host/Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide with sequence C-PDNINEGQVQVRT (aa 31–43) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Wet ice |
| RRID | AB_2933924 |
Product Specific Information
This antibody has been tested in Peptide ELISA with an antibody detection limit dilution of 1:128,000.
Target Information
ZADH1 (zinc binding alcohol dehydrogenase, domain containing 1), also known as PTGR2 (prostaglandin reductase 2), PGR2, or 15-oxoprostaglandin 13-reductase, is a 351-amino-acid cytoplasmic protein belonging to the NADP-dependent oxidoreductase L4BD family.
Functioning as a 15-oxoprostaglandin 13-reductase, ZADH1 catalyzes the conversion of 15-keto-prostaglandin E2 to 15-keto-13,14-dihydro-prostaglandin E2 in a NADPH-dependent manner. Overexpression of ZADH1 represses PPAR gamma transcriptional activity and adipocyte differentiation.
ZADH1 is widely expressed, with highest levels in heart, kidney, liver, pancreas, and prostate, and moderate levels in brain, small intestine, lung, testis, and skeletal muscle. It exists as a monomer, utilizes NADPH as a cofactor, and undergoes alternative splicing to produce two isoforms encoded by a gene located on human chromosome 14q24.3.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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