Thermo Fisher Scientific FKBP6 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

0.04-0.4 µg/mL

-

Immunohistochemistry (Paraffin) (IHC (P))

1:200-1:500

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human FKBP6. Recombinant protein control fragment (Product #RP-103389). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:FKBP6,uniProtId:O75344-1,ncbiNodeId:9606,antigenRange:113-197,antigenLength:327,antigenImageFileName:PA5-63926_FKBP6_O75344-1_Rabbit.svg,antigenImageFileNamePDP:PA5-63926_FKBP6_O75344-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.05 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2641656

Product Specific Information

Immunogen sequence: KPNYAYGTLG CPPLIPPNTT VLFEIELLDF LDCAESDKFC ALSAEQQDQF PLQKVLKVAA TEREFGNYLF RQNRFYDAKV RYKRA

Highest antigen sequence identity to the following orthologs: Mouse - 93%, Rat - 93%.

Target Information

FKBP6 is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. FKBP6 is a cis-trans prolyl isomerase that binds to the immunosuppressants FK506 and rapamycin.This gene encodes a member of the interferon regulatory transcription factor (IRF) family. Family members share a highly-conserved N-terminal helix-turn-helix DNA-binding domain and a less conserved C-terminal protein-binding domain. Mutations in this gene can cause van der Woude syndrome and popliteal pterygium syndrome. This protein is involved in palate formation.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.