Thermo Fisher Scientific NUCB2 Polyclonal Antibody
NUCB2 단백질을 인식하는 토끼 폴리클로날 항체로, Western blot 및 Immunoprecipitation에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, 1 mg/mL 농도의 액상 형태입니다. 인간 시료에 반응하며 연구용으로 사용됩니다.
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Applications
Western Blot (WB)
- Assay-dependent
Immunoprecipitation (IP)
- 2–10 µg/mg lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 175 to 225 of human Nucleobindin-2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | Phosphate/tris citrate, pH 7–8 |
| Contains | 0.09% sodium azide |
| Storage conditions | 4°C |
| Shipping conditions | Wet ice |
Product Specific Information
The recommended shelf life for this product is 1 year from date of receipt.
Target Information
NUCB2 (Nucleobindin-2) is a calcium-binding protein containing an EF-hand motif that interacts with Necdin, a growth suppressor expressed mainly in postmitotic neurons. NUCB2 is secreted and cleaved into three major peptide products — Nesfatin-1, Nesfatin-2, and Nesfatin-3.
Nesfatin-1 is known to suppress food intake in a leptin-independent manner. Studies suggest that NUCB2/Nesfatin-1 plays roles in energy homeostasis and neuroendocrine regulation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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