Thermo Fisher Scientific DLC1 Polyclonal Antibody
DLC1 단백질 인식용 Goat Polyclonal Antibody로, Western Blot, IHC, ICC/IF에 사용 가능. 인간 및 생쥐 반응성. 암 억제 관련 GTPase-activating 단백질 연구에 적합. 고순도 액상 형태로 -20°C 보관.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | - | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 4 µg/mL | - |
| Immunocytochemistry (ICC/IF) | 10 µg/mL | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Published Species | Not Applicable |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide sequence (SVAIRKRSWEEHC) corresponding to the N-terminus amino acids of DLC1 (aa 2-13) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_10977215 |
Product Specific Information
- Predicted to react with mouse and porcine based on sequence homology.
- Tested in Peptide ELISA: antibody detection limit dilution 64,000.
Target Information
This gene encodes a GTPase-activating protein that is a member of the rhoGAP family of proteins, which regulate small GTP-binding proteins. GAP family proteins participate in signaling pathways that control cytoskeletal changes.
This gene functions as a tumor suppressor in various cancers, including prostate, lung, colorectal, and breast cancers.
Multiple transcript variants have been identified due to alternative promoters and splicing.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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