Thermo Fisher Scientific PTPRB Polyclonal Antibody
Human PTPRB 단백질을 인식하는 염소 유래 폴리클로날 항체. ICC/IF 및 유세포분석에 적합하며, 비결합형 액상 형태로 제공. 0.5 mg/mL 농도, TBS(pH 7.3) 버퍼에 0.5% BSA 포함. 세포 성장 및 신호전달 연구용으로 적합.
- 카탈로그번호
- PA5142590
- 판매단위
- pk
카탈로그
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunocytochemistry (ICC/IF) | 10 µg/mL |
| Flow Cytometry (Flow) | 10 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide with sequence C-ENHSFSQERTVPDK |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2933236 |
Product Specific Information
This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:16,000.
Target Information
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are signaling molecules that regulate cellular processes such as cell growth, differentiation, mitotic cycle, and oncogenic transformation.
This PTP contains an extracellular domain, a single transmembrane segment, and one intracytoplasmic catalytic domain, classifying it as a receptor-type PTP.
The extracellular region includes multiple fibronectin type III repeats, which interact with neuronal receptors and cell adhesion molecules such as contactin and tenascin C.
It also interacts with sodium channels, potentially regulating them via tyrosine phosphorylation status.
These interactions suggest roles in cell adhesion, neurite growth, and neuronal differentiation.
Alternate transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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