Thermo Fisher Scientific B4GALT4 Polyclonal Antibody
Human B4GALT4 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot과 IHC(P)에서 검증됨. 항원 친화 크로마토그래피로 정제되었으며, PBS buffer와 glycerol로 안정화. 연구용으로 glycolipid 생합성 연구에 적합.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human B4GALT4. Recombinant protein control fragment (Product # RP-90163) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.3 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2638442 |
Product Specific Information
Immunogen sequence:
AIQEIPKAKE FMANFHKTLI LGKGKTLTNE ASTKKVELDN CPSVSPYLRG QSKLIFKPDL TLEEVQAENP KVSRGRYRPQ ECKALQRVAI LVPHRNREKH LMYLLEHLHP F
Highest antigen sequence identity to the following orthologs:
- Mouse: 78%
- Rat: 77%
Target Information
This gene is one of seven beta-1,4-galactosyltransferase (beta4GalT) genes. These encode type II membrane-bound glycoproteins with specificity for the donor substrate UDP-galactose, transferring galactose in a beta1,4 linkage to acceptor sugars such as GlcNAc, Glc, and Xyl.
Each beta4GalT plays a distinct role in the biosynthesis of various glycoconjugates and saccharide structures. As type II membrane proteins, they possess an N-terminal hydrophobic signal sequence that directs localization to the Golgi apparatus and functions as a transmembrane anchor.
The enzyme encoded by this gene primarily participates in glycolipid biosynthesis. Two alternatively spliced transcript variants have been identified for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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