Thermo Fisher Scientific OX40/CD134/TNFRSF4 (Immuno-Oncology Target) Monoclonal Antibody (OX40/3428)

Applications

Tested Dilution

Publications

ELISA (ELISA)

Assay-dependent

-

Peptide Array (Array)

Assay-dependent

-

Product Specifications

Species Reactivity

Chimpanzee, Human

Host/Isotype

Mouse / IgG1, kappa

Class

Monoclonal

Type

Antibody

Clone

OX40/3428

Immunogen

Recombinant fragment of human OX40 (CD134) protein (around aa 59-205). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:OX40 (CD134),uniProtId:P43489-1,ncbiNodeId:9606,antigenRange:59-205,antigenLength:277,antigenImageFileName:7293-MSM8-P1ABX_OX40_CD134_P43489-1_House_mouse.svg,antigenImageFileNamePDP:7293-MSM8-P1ABX_OX40_CD134_P43489-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Protein A/G

Storage buffer

PBS, pH 7.4

Contains

no preservative

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

Target Information

OX40 is a protein receptor found on the surface of T cells, a type of white blood cell that plays a crucial role in the immune system. When activated, OX40 promotes the proliferation and survival of T cells, leading to a stronger immune response against cancer cells and infectious agents. OX40 agonists, which are drugs that activate OX40, have shown promising results in preclinical and clinical studies as a potential immunotherapy for cancer. They can enhance the efficacy of other cancer treatments such as chemotherapy and checkpoint inhibitors, and may also have applications in autoimmune diseases and allergies.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.