Thermo Fisher Scientific HNF4A Polyclonal Antibody
HNF4A 단백질을 인식하는 Goat Polyclonal Antibody로 Western blot과 IHC(P) 실험에 적합. 인간 반응성, 액상 형태, 0.5 mg/mL 농도. 간, 신장, 장, 췌장에서 발현되는 HNF4α 연구용으로 사용.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.1–0.5 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide sequence (RLSKTLVDMDMADY) corresponding to the N-terminus amino acids of HNF4A (aa 2–15) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_10988302 |
Product Specific Information
- Predicted to react with canine and porcine based on sequence homology.
- Tested in Peptide ELISA: antibody detection limit dilution 32,000.
Target Information
Hepatocyte nuclear factor 4 alpha (HNF4α) is an orphan nuclear receptor expressed in the liver, kidney, intestine, and pancreas.
Mutation of HNF4α in humans has been associated with maturity-onset diabetes of the young type 1 (MODY1).
HNF4 binds to DNA as an exclusive homodimer. The HNF4α gene is alternatively spliced and may generate up to nine different isoforms (HNF4α1–HNF4α9).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일: PA5-18363_HNF4A_P41235-1_Goat.svg, PA5-18363_HNF4A_P41235-1_Goat_PDP.jpeg)
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