Thermo Fisher Scientific MTHFD2 Monoclonal Antibody (S1)
인간 MTHFD2 단백질을 표적으로 하는 Mouse IgG2a monoclonal antibody. Western blot, IHC, ELISA에 사용 가능. 고순도 친화 크로마토그래피 정제, PBS buffer 보존, 연구용 전용 시약.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | Assay-Dependent |
| Immunohistochemistry (Paraffin) (IHC (P)) | 3 µg/mL |
| ELISA | 10 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | S1 |
| Immunogen | MTHFD2 (AAH01548, 16 a.a. approximately 344 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
SLRLRPFHLA AVRNEAVVIS GRKLAQQIKQ EVRQEVEEWV ASGNKRPHLS VILVGENPAS HSYVLNKTRA AAVVGINSET IMKPASISEE ELLNLINKLN NDDNVDGLLV QLPLPEHIDE RRICNAVSPD KDVDGFHVIN VGRMCLDQYS MLPATPWGVW EIIKRTGIPT LGKNVVVAGR SKNVGMPIAM LLHTDGAHER PGGDATVTIS HRYTPKEQLK KHTILADIVI SAAGIPNLIT ADMIKEGAAV IDVGINRVHD PVTAKPKLVG DVDFEGVRQK AGYITPVPGG VGPMTVAMLM KNTIIAAKKV LRLEEREVLK SKELGVATN
Target Information
This gene encodes a nuclear-encoded mitochondrial bifunctional enzyme with methylenetetrahydrofolate dehydrogenase and methenyltetrahydrofolate cyclohydrolase activities. The enzyme functions as a homodimer and is unique in its absolute requirement for magnesium and inorganic phosphate. Formation of the enzyme-magnesium complex allows binding of NAD. Alternative splicing results in two different transcripts, one protein-coding and the other not protein-coding. This gene has a pseudogene on chromosome 7.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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