Thermo Fisher Scientific NBPF Pan Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

-

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

-

Immunocytochemistry (ICC/IF)

1:100-1:500

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

A synthesized peptide derived from human NBPF1(Accession Q3BBV0), corresponding to amino acid residues L1075-E1125. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:NBPF Pan,uniProtId:Q3BBV0-1,ncbiNodeId:9606,antigenRange:1075-1125|1214,antigenLength:1214,antigenImageFileName:PA5-101712_NBPF_Pan_Q3BBV0-1_Rabbit.svg,antigenImageFileNamePDP:PA5-101712_NBPF_Pan_Q3BBV0-1_Rabbit_PDP.jpeg,sortOrder:1},{targetFamily:NBPF Pan,uniProtId:P0DPF3-1,ncbiNodeId:9606,antigenRange:1111,antigenLength:1111,antigenImageFileName:PA5-101712_NBPF_Pan_P0DPF3-1_Rabbit.svg,antigenImageFileNamePDP:PA5-101712_NBPF_Pan_P0DPF3-1_Rabbit_PDP.jpeg,sortOrder:2},{targetFamily:NBPF Pan,uniProtId:Q5TAG4-1,ncbiNodeId:9606,antigenRange:1457,antigenLength:1457,antigenImageFileName:PA5-101712_NBPF_Pan_Q5TAG4-1_Rabbit.svg,antigenImageFileNamePDP:PA5-101712_NBPF_Pan_Q5TAG4-1_Rabbit_PDP.jpeg,sortOrder:3},{targetFamily:NBPF Pan,uniProtId:Q5TI25-1,ncbiNodeId:9606,antigenRange:921,antigenLength:921,antigenImageFileName:PA5-101712_NBPF_Pan_Q5TI25-1_Rabbit.svg,antigenImageFileNamePDP:PA5-101712_NBPF_Pan_Q5TI25-1_Rabbit_PDP.jpeg,sortOrder:4},{targetFamily:NBPF Pan,uniProtId:Q6P3W6-1,ncbiNodeId:9606,antigenRange:3795,antigenLength:3795,antigenImageFileName:PA5-101712_NBPF_Pan_Q6P3W6-1_Rabbit.svg,antigenImageFileNamePDP:PA5-101712_NBPF_Pan_Q6P3W6-1_Rabbit_PDP.jpeg,sortOrder:5},{targetFamily:NBPF Pan,uniProtId:Q8N660-1,ncbiNodeId:9606,antigenRange:670,antigenLength:670,antigenImageFileName:PA5-101712_NBPF_Pan_Q8N660-1_Rabbit.svg,antigenImageFileNamePDP:PA5-101712_NBPF_Pan_Q8N660-1_Rabbit_PDP.jpeg,sortOrder:6}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.4, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice

RRID

AB_2815892

Product Specific Information

Antibody detects endogenous levels of total NBPF1/9/10/12/14/15/16/20.

Target Information

This gene is a member of the neuroblastoma breakpoint family (NBPF) which consists of dozens of recently duplicated genes primarily located in segmental duplications on human chromosome 1. This gene family has experienced its greatest expansion within the human lineage and has expanded, to a lesser extent, among primates in general. Members of this gene family are characterized by tandemly repeated copies of DUF1220 protein domains. Gene copy number variations in the human chromosomal region 1q21.1, where most DUF1220 domains are located, have been implicated in a number of developmental and neurogenetic diseases such as microcephaly, macrocephaly, autism, schizophrenia, mental retardation, congenital heart disease, neuroblastoma, and congenital kidney and urinary tract anomalies. Altered expression of some gene family members is associated with several types of cancer. This gene family contains numerous pseudogenes. [provided by RefSeq, Apr 2013].

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.