Thermo Fisher Scientific NBPF Pan Polyclonal Antibody
NBPF 단백질군을 인식하는 Rabbit Polyclonal Antibody로, WB, IHC(P), ICC/IF에 사용 가능. Human, Mouse, Rat에 반응하며, Affinity Chromatography로 정제됨. PBS/glycerol buffer에 보관되며 -20°C에서 안정적. 연구용으로 적합.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human NBPF1 (Accession Q3BBV0), corresponding to amino acid residues L1075–E1125 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2815892 |
Product Specific Information
Antibody detects endogenous levels of total NBPF1/9/10/12/14/15/16/20.
Target Information
The NBPF (Neuroblastoma Breakpoint Family) gene family consists of numerous recently duplicated genes primarily located on human chromosome 1. These genes contain tandemly repeated DUF1220 protein domains. Copy number variations in the 1q21.1 region, where DUF1220 domains are located, have been linked to developmental and neurogenetic disorders such as microcephaly, macrocephaly, autism, schizophrenia, congenital heart disease, and neuroblastoma. Altered expression of NBPF family members has also been associated with various cancers. This gene family includes multiple pseudogenes.
[provided by RefSeq, Apr 2013]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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