Thermo Fisher Scientific OGG1 Recombinant Rabbit Monoclonal Antibody (ARC1233)
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카탈로그 번호 | CAS 번호 | 설명 | 상태 | 재고 | 단위 | 판매가 | 할인가 | 가격(VAT포함) | 수량 / 장바구니 / 찜 |
MA535616 | - | Thermo Fisher Scientific MA535616 OGG1 Recombinant Rabbit Monoclonal Antibody (ARC1233) 100 ul pk | 재고문의 | pk | 612,000원 | - | 673,200원 |
다른 상품 둘러보기
Applications
Tested Dilution
Publications
Western Blot (WB)
1:500-1:2,000
Immunohistochemistry (Paraffin) (IHC (P))
1:100-1:1,000
ELISA (ELISA)
1 µg/mL
Product Specifications
Species Reactivity
Human, Mouse, Rat
Host/Isotype
Rabbit / IgG
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
ARC1233
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 246-345 of human OGG1 (O15527) if (typeof window.$mangular === undefined
|| !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{
targetFamily:
OGG1,
uniProtId:
O15527-1,
ncbiNodeId:
9606,
antigenRange:
246-345,
antigenLength:
345,
antigenImageFileName:
MA5-35616_OGG1_O15527-1_Rabbit.svg,
antigenImageFileNamePDP:
MA5-35616_OGG1_O15527-1_Rabbit_PDP.jpeg,
sortOrder:
1}\]
; $mangular.isB2BCMGT = false
; $mangular.isEpitopesModalImageMultiSizeEnabled = true
;
View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}
Conjugate
Unconjugated Unconjugated Unconjugated
Form
Liquid
Concentration
0.50 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol, 0.05% BSA
Contains
0.02% sodium azide
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2849516
Product Specific Information
Immunogen sequence: VGTKVADCIC LMALDKPQAV PVDVHMWHIA QRDYSWHPTT SQAKGPSPQT NKELGNFFRS LWGPYAGWAQ AVLFSADLRQ SRHAQEPPAK RRKGSKGPEG
Target Information
8-hydroxyguanine, a form of oxidative DNA damage induced by free radicals, causes G:C to T:A transversion. In E. Coli, three DNA repair enzymes exist to prevent the mutagenic effects of 8-hydroxyguanine. One of these enzymes, MutM, was found to have a functional yeast (yOgg1) and human (hOgg1) homologue. hOgg1 proteins efficiently released the 8-hydroxyguanine opposite the pyrimidine from DNA and cleaved the AP site in a manner similar to bacterial and yeast enzymes. Genetic backgrounds in control of the repair of damaged DNA are involved in the susceptibility to cancer development. The hOgg1 gene has been mapped to region 3p26. 2, a region showing loss of heterozygosity (LOH) in a variety of cancers. In particular, 3p25-p26 is a common LOH region in lung cancer.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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