
Thermo Fisher Scientific TFPI Monoclonal Antibody (OTI2B10), TrueMAB
인간 TFPI 단백질을 인식하는 단클론 항체로, Western blot에 적합합니다. E. coli에서 생산된 재조합 단백질을 면역원으로 사용하였으며, 동결건조 형태로 제공됩니다. 고순도 친화 크로마토그래피로 정제되었으며, 연구용으로만 사용 가능합니다.
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Applications
Tested Application
- Western Blot (WB): 1:2,000 dilution
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2B10 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 29–304 of human TFPI produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- For reconstitution, add 100 µL of distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
- For conjugation experiments, perform an additional desalting step (Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
Tissue factor pathway inhibitor (TFPI), also known as lipoprotein-associated coagulation inhibitor, is a protease inhibitor that regulates the tissue factor (TF)-dependent pathway of blood coagulation. TFPI is glycosylated and predominantly found in the vascular endothelium and plasma in both free and lipoprotein-bound forms. It inhibits activated factor X and the VIIa–TF complex in an autoregulatory loop, thereby modulating fibrin clot formation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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